citation_inspection: 180

Review of Protocol 22-01: The protocol includes major operative procedures on sheep. The dose and frequency of administration of the post-operative analgesic included in the protocol approved by the IACUC is not adequate to avoid or minimize discomfort, distress, and pain in the animals. The post-operative dose for Buprenorphine in the IACUC approved protocol was 0.18 mg once a day for 3 days. Per this Section, the IACUC shall determine during the review of the proposed animal use activities or significant changes to ongoing activities, that procedures that may cause more that momentary pain or distress to the animals will be performed with appropriate sedatives, analgesics, or anesthetics unless withholding such agents is justified by the principal investigator for scientific reasons. The IACUC needs to address this deficiency that was identified for this protocol. Correct by 5/27/22.