citation_inspection: 154

***On August 2, 2016 three (3) African Green Monkeys on study 16-054 died following a bronchial alveolar gavage procedure. One (1) was found dead and the other two were in respiratory distress and expired after unsuccessful attempts to revive them. The following day, August 3, 2016, five (5) additional African Green Monkeys on the study were found dead during the morning health check. Four (4) African Green Monkeys on the study remain and have not demonstrated any signs of illness or distress. Post-procedural monitoring was conducted per SOP during normal work hours, however no additional monitoring of the remaining nine (9) non-human primates on the study was conducted overnight. Due to the recent deaths of the non-human primates on study, more frequent monitoring may have allowed for more immediate intervention to prevent the deaths of the remaining animals on the study. Procedures must be established and implemented to ensure adequate monitoring of study animals following an adverse event. Correct by December 30, 2016. This inspection and exit interview were conducted with the Director / IACUC Chair. This is an electronic copy of the Microsoft Word report dated 29 November 2016.